Biology Immunology Multiple Choice Essay Questions

Biology Immunology Multiple Choice Essay Questions

ESSAY- ID	53563633773
Type	Essay
Writer Level	Masters
Style	APA
Sources/References	4
Perfect Number of Pages to ESSAY-	5-10 Pages

Description/Paper Instructions

Biology Immunology Multiple Choice Essay Questions

In order to diagnose Mycobacterium tuberculosis (MTB) infection, doctors commonly perform the Mantoux. it involves injecting tuberculin antigens (a glycerol extract of MTB) under the skin and waiting for 24 – 48h for the development of a swollen red lump at the injection site. The presence of a positive reaction after 24h in an MTB-infected patient would be due to which of the following:

Select one:

a.

Re-activation of existing MTB-specific TH1 responses at the site of injection

b.

Triggering of mast cell degranulation due to binding of MTB-specific IgE at the site of injection

c.

Re-activation of existing MTB-specific CD8 T cell responses at the site of injection

d.

Recruitment of neutrophils after release of IL-8 from resting macrophages

e.

Complement-mediated lysis of macrophages binding to tuberculin at the site of injection

Lymphocyte anergy to self-antigens is defined as?

Select one:

a.

Elimination of self-reactive lymphocytes from the body before activation

b.

Apoptosis of self-reactive lymphocytes after activation

c.

Activation of self-reactive lymphocytes after antigen encounter

d.

Inactivation of self-reactive lymphocytes after antigen encounter

Central tolerance of T cells towards self-antigens develops where?

Select one:

a.

In the thymus in early life

b.

In the thymus after infection

c.

In the spleen and lymph nodes

d.

In the gut in early life

e.

After peripheral tolerance has failed

IgM is a key defense molecule found in serum and crosses the placenta in the last trimester of pregnancy to provide the newborn human with passive immunity from its mother.

Select one:

1. True
2. False
3. Only in some pregnancies

Rejection of a xenograft (a graft from a different species) would most likely be caused by which of the following?

Select one:

a.CD4 and CD8 effector T cell responses that develop within weeks

1. Pre-existing, cross-reactive antibodies against the graft
2. Development of anti-graft antibodies over time
3. Memory CD8 responses present from previous grafts
4. NK cell responses against graft MHC molecules

Glycoconjugate vaccines (where polysaccharide antigens from a pathogen are chemically linked to a protein antigen) are a major breakthrough in infant/childhood vaccination because they?

Select one:

a . Allow better anti-protein responses to encapsulated bacteria

b.

Enable strong and lasting IgM responses to be induced

c.

Covert T-independent responses into T-dependent responses

d.

Engage cytotoxic T cells as well as antibody production

e.

Allow children to make IgE responses to polysaccharide antigens

You are asked to help diagnose a patient presenting with severe, recurrent Staphylococcus aureus infections of the synovial fluid around the knees. When considering possible immunological explanations for this patient’s condition, which of the following conditions should you consider first?

Select one:

a.

Primary deficiencies of phagocyte function

b.

Primary deficiencies of NK function

c.

Primary deficiencies of antibody function

d.

Primary deficiencies of lymphocyte function

e.

An acquired immune deficiency

Allograft transplantation occurs when a donor receives an organ/graft from?

Select one:

a.

An identical twin

b.

Some other site on their body

c.

A different donor of the same species

d.

A different donor of a different species

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